Category: "Bioinformatics"

1000 Genomes Project Populations

April 3rd, 2012
The goal of the 1000 Genomes Project is create a "A Deep Catalog of Human Genetic Variation " by measuring and analysing most genetic variants that have frequencies of at least 1% in the populations studied. The population codes used in the project… more »

Canonical transcripts

January 3rd, 2012
As reported in the Ensembl 2009 NAR paper canonical transcripts are defined for all genes and for all species in the Ensembl gene sets. "The canonical transcript is defined as either the longest CDS, if the gene has translated transcripts, or the longes… more »

Telomeric and Centromeric regions

September 22nd, 2011
Telomeres form caps on the ends of chromosomes that prevent fusion of chromosomal ends and provide genomic stability. During gametogenesis, reprogramming of the germ cells leads to elongation of telomeres up to their species-specific maximum. In nor… more »

Cytogenetic Nomenclature

September 6th, 2011
The karyotype (number and set-up of the chromosomes) of a person or any changes in specific regions on human chromosomes are described with a system of numbers and symbols, defined by a group of cytogentic experts as the International System for Human C… more »

SQLite

June 3rd, 2011
Using the SQLite database Engine SQLite is different (to MySQL) in a number of ways, the main one bein that it is server-less. The other differences are nicely listed here with pros and cons. more »