Category: "Biology"

Male infertility genetics

August 17th, 2012
10-15% of couples are faced with some kind of infertility issue, in almost half the cases there are (co-)factors on the male side. Male infertility factors are often based on sperm abnormalities which can be categorized into more »

Analysing Variation with Ensembl and PolyPhen

May 28th, 2012
The Ensembl variation resources provide information about structural variants and sequence variants (including Single Nucleotide Polymorphisms (SNPs), insertions, deletions and somatic mutations in the human genome. more »

Genometastasis

May 9th, 2012
The hypothesis of genometastasis was suggested by GarcĂ­a-Olmo et al. more than a decade ago (1) and states (simplified) that normal cells could be turned into cancer cells through contact with (dying) cancer cells. more »

Uniparental Disomy

May 4th, 2012
In cases where two copies of the same chromosome, or part of a chromosome, from one parent and no copies from the other parent are present in the cell, we call it uniparental disomy (UPD). While all DNA information is present, the development of the cel… more »

Nucleotide Ambiguity Codes

April 4th, 2012
IUPAC nucleotide ambiguity codes ------------------------------------------ Symbol Meaning Nucleic Acid ------------------------------------------ A A Adenine C C Cytosine G G… more »