Category: "Genomics"

Sequence Mappability & Alignability

May 16th, 2012
Sequence uniqueness and the possbility to map sequence parts (e.g. NGS short reads) back to a genomic region... The CRG Alignability tracks display how uniquely k-mer sequences align to a region of the genome. For each window (of sizes 36, 40, 50, 75… more »

Genometastasis

May 9th, 2012
The hypothesis of genometastasis was suggested by GarcĂ­a-Olmo et al. more than a decade ago (1) and states (simplified) that normal cells could be turned into cancer cells through contact with (dying) cancer cells. more »

OMIM Symbols

April 16th, 2012
The Online Mendelian Inheritance in Man is a manually reviewed catalog of human genes and genetic disorders and traits. Each entry has a name and a number, e.g. "#154780 MARSHALL SYNDROME". According to the OMIM FAQs, these are the meanings of the the s… more »

Telomeric and Centromeric regions

September 22nd, 2011
Telomeres form caps on the ends of chromosomes that prevent fusion of chromosomal ends and provide genomic stability. During gametogenesis, reprogramming of the germ cells leads to elongation of telomeres up to their species-specific maximum. In nor… more »

PAR regions

April 6th, 2011
To pull out the coordinates of the pseudo-autosomal regions from the Ensembl database, you can perform the following query on the core database: select sr.name as chromosome, ae.seq_region_start as start, ae.seq_region_end as end from assembly_exceptio… more »